GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs12220238 | 1 | rs73284257 | chr10:76000710 | ADK | chr10:75910965-76469059:+ | 0.28 | 4.19 | 3.41E-5 | Soluble interleukin-2 receptor subunit alpha |
| BLCA | cis | rs7327064 | 1 | rs7331697 | chr13:36763345 | SOHLH2 | chr13:36742347-36871992:- | -0.39 | -5.08 | 6.03E-7 | Economic and political preferences |
| BLCA | cis | rs2149423 | 1 | rs7332189 | chr13:36755610 | SOHLH2 | chr13:36742347-36871992:- | -0.26 | -4.35 | 1.72E-5 | Glucose homeostasis traits |
| BLCA | cis | rs2149423 | 1 | rs7332932 | chr13:36755636 | SOHLH2 | chr13:36742347-36871992:- | -0.26 | -4.35 | 1.72E-5 | Glucose homeostasis traits |
| BLCA | cis | rs13053817 | 1 | rs73405097 | chr22:29855836 | MTMR3 | chr22:30279158-30426855:+ | 0.24 | 3.84 | 0.000142 | Carotid atherosclerosis in HIV infection |
| BLCA | cis | rs13053817 | 1 | rs73405097 | chr22:29855836 | NIPSNAP1 | chr22:29950800-29977144:- | 0.28 | 4.02 | 6.98E-5 | Carotid atherosclerosis in HIV infection |
| BLCA | cis | rs4494548 | 1 | rs73543347 | chr16:20385774 | DCUN1D3 | chr16:20869403-20911561:- | -0.41 | -3.89 | 0.00012 | Urinary uromodulin levels |
| BLCA | cis | rs4494548 | 1 | rs73543347 | chr16:20385774 | THUMPD1 | chr16:20744991-20753199:- | -0.39 | -4.08 | 5.58E-5 | Urinary uromodulin levels |
| BLCA | cis | rs10935120 | 1 | rs7356093 | chr3:134238753 | ANAPC13 | chr3:134196547-134204865:- | 0.5 | 7.88 | 3.42E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs7356093 | chr3:134238753 | CEP63 | chr3:134204575-134293852:+ | 0.24 | 4.04 | 6.44E-5 | Height |
| BLCA | cis | rs737008 | 1 | rs737008 | chr16:11374866 | C16orf75 | chr16:11343506-11445617:+ | 0.2 | 3.88 | 0.000124 | Obesity-related traits |
| BLCA | cis | rs10935120 | 1 | rs7371896 | chr3:134249769 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.77 | 7.23E-14 | Height |
| BLCA | cis | rs9815354 | 1 | rs7372217 | chr3:41990122 | ULK4 | chr3:41288091-42003660:- | -0.63 | -9.71 | 4.41E-20 | Diastolic blood pressure |
| BLCA | cis | rs10935120 | 1 | rs7374158 | chr3:134270156 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.7 | 1.15E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs7374158 | chr3:134270156 | CEP63 | chr3:134204575-134293852:+ | 0.23 | 3.93 | 0.000102 | Height |